Cholesterol and Metabolism Center Research and Studies

Recent Publications

• Vitamin D deficiency, myositis-myalgia, and reversible statin intolerance
• Symptomatic myositis-myalgia in hypercholesterolemic statin-treated patients with concurrent vitamin D deficiency leading to statin intolerance may reflect a reversible interaction between vitamin D deficiency and statins on skeletal muscle
• Thrombotic events after starting exogenous testosterone in men with previously undiagnosed familial thrombophilia
• PCOS, Body Owner's Guide
• Study Protocol: Exogenous Testosterone and venous thrombosis in Patients with Underlying Clotting abnormalities
• Childhood Predictors of Adult Type 2 Diabetes at 9- and 26-Year Follow-ups
• Metformin-Diet Ameliorates Coronary Heart Disease Risk Fasctors and Facilitates Resumption of Regular Menses in Adolescents with Polycystic Ovary Syndrome
• Preteen insulin levels interact with caloric intake to predict increases in obesity at ages 18 to 19 years: a 10-year prospective study of black and white girls

Guidelines for Interpreting Results from Health Screening

• Health Screening Recommendations
• Guidelines to Interpret Results from Health Screening

Nutrition - Vitamins and Health

• Biomarkers predictive of inflammatory processes in acute clinical settings
• Dietary Supplements: A Position Paper for Jewish Hospital Cholesterol Center

Cholesterol Diagnosis and Therapy, 2009

• Low serum 25 (OH) vitamin D levels are associated with reversible myositis-myalgia in statin-treated patients
• Vitamin D
• Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia?

Insulin, obesity, and early development of type 2 diabetes mellitus:

• Pre-teen insulin resistance predicts weight gain, impaired fasting glucose, and type 2 diabetes at age 18-19 y: a 10-y prospective study of black and white girls.
• J Pediatr Endocrinol Metab.
• Long Term Metabolic Complications of Childhood Obesity

Reproduction, Miscarriage and Cardiovascular Health in Women:

• PCOS, Body Owner's Guide
• Should Women After Hysterectomy Take Estrogen Supplementation?
• Why do women have sporadic miscarriage? A new, clinical research study.
• Hormones and Heart Disease 
• Repetitive Pregnancy Loss / Very Early Pregnancy Loss
• PolyCystic Ovary Syndrome (PCOS)
• Paradigms Lost, 2005-2006
• Estrogen Supplementation in Post Menopausal Women
• Estrogen Replacement Therapy
• Hormone Replacement Therapy (HRT): The Good, The Bad and The Ugly
• Estrogen and Triglycerides
• Enoxaparin-metformin and enoxaparin alone may safely reduce pregnancy loss

Other Cardiovascular:

• Prinzmetal's Angina Press Release
• Prinzmetal's Angina, History, Diagnosis, Treatment

Diagnosis & Treatment of Cholesterol & Triglyceride Disorders:

• Lipids Are...
• Treating High Cholesterol After Age 65
• Treating High Cholesterol in Children
• Risk Assessment for Heart Attack and Stroke
• Diagnosis and Therapy of Risk Factors for Ischemic Stroke
• How Low Should Cholesterol Go?
• How Low Should Cholesterol Go? (Scientific Update 1/30/08 - Optimal LDL Cholesterol < 70 MG/DL)
• How Low Should Cholesterol Go? (2009)
• Role of LDL Cholesterol, HDL Cholesterol and Triglcerides in the prevention of coronary heart disease and stroke
• Triglycerides, low HDL Cholesterol, Coronary Heart Disease, Stroke, and Pancreatitis: Diagnosis and Therapy
• Triglycerides, coronary heart disease, and stroke: diagnosis and treatment, 2009
• Exercise and Cardiovascular Disease
• Free Triglyceride Lowering Study

Osteonecrosis:

• Osteonecrosis
• Study on Therapy of Osteonecrosis
• Thrombophilia-Hypofibrinolysis, reduced Nitric Oxide Production, and Osteonecrosis - 2009 Update
  

Insulin Resistance & Diabetes:

• Insulin Resistance and Hyperinsulinemia
• Metformin and Gestational Diabetes
• Prevention of Gestational Diabetes

Coagulation (Blood Clotting) Disorders:

• Ocular Thrombosis 2010
• Retinal Vein Thrombosis and Visual Problems
• Venous and Arterial Thrombosis
• Thrombophilia and hypofibrinolysis: Pathoetiologies of Pseudotumor Cerebri
• Thrombophilia and hypofibrinolysis: Pathoetiologies for Retinal Artery Thrombosis
• Thrombophilia and hypofibrinolysis: Pathoetiologies of Amaurosis Fugax
• Molecular Diagnosis of Risk Factors for Venous and Arterial Thrombosis, and Atherosclerosis at www.mdl-labs.com
• Treatment of Crohn's Disease with Heparin
• Ocular Thrombosis: a Hypercoagulable Disease
• Ocular vascular thrombotic events: a diagnostic window to familial thrombophilia (compound Factor V Leiden and Prothrombin gene heterozygosity) and thrombosis.
• Ocular vascular thrombotic events: central retinal vein and central retinal artery occlusions.

Buerger's Disease:

• Buerger's Disease, History, Diagnosis, Treatment 
• Oral L-arginine Supplement and Nitric Oxide Generation: Implication in Vascular Health
• Endothelial Nitric Oxide Synthase (eNOS) Polymorphism
• The stromelysin-1 5A/6A promoter polymorphism

Hypogonadism:

• Male Hypogonadism